Challenges Faced by Women with Cystic Fibrosis

Raksha Jain; Traci M Kazmerski; Moira L Aitken; Natalie West; Alexandra Wilson; Kubra M Bozkanat; Kristina Montemayor; Karen von Berg; Jacqui Sjoberg; Maddie Poranski; Jennifer L Taylor-Cousar

doi:10.1016/j.ccm.2021.04.010

Challenges Faced by Women with Cystic Fibrosis

Clin Chest Med. 2021 Sep;42(3):517-530. doi: 10.1016/j.ccm.2021.04.010.

Authors

Affiliations

¹ Department of Medicine, University of Texas Southwestern, 5323 Harry Hines Boulevard, Dallas, TX 75390-8558, USA. Electronic address: [email protected].
² Department of Pediatrics, University of Pittsburgh School of Medicine, 120 Lytton Avenue Suite M060 University Center, Pittsburgh, PA 15213, USA.
³ Department of Medicine, University of Washington, 1959 NE Pacific Street - Room BB 1361, Seattle, WA 98195-6522, USA.
⁴ Department of Medicine, Johns Hopkins University, 1830 East Monument Street, 5th Floor, Baltimore, MD 21205, USA.
⁵ Department of Medicine, Cystic Fibrosis Clinical Research, National Jewish Health, 1400 Jackson Street, K333b, Denver, CO 80206, USA.
⁶ Department of Pediatrics, University of Texas Southwestern, 5323 Harry Hines Boulevard, Dallas, TX 75390-8558, USA.
⁷ Department of Physical Medicine and Rehabilitation, Johns Hopkins Hospital, 1800 Orleans Street, Baltimore, MD 21287, USA.
⁸ Adult with Cystic Fibrosis, 237 Russell Street, Oceanside, CA 92058, USA.
⁹ Adult with Cystic Fibrosis, 2700 University Avenue West Apartment 416, St Paul, MN 55114, USA.
¹⁰ Department of Medicine, National Jewish Health, 1400 Jackson Street; J318, Denver, CO 80206, USA; Department of Pediatrics, National Jewish Health, 1400 Jackson Street; J318, Denver, CO 80206, USA.

PMID: 34353456
DOI: 10.1016/j.ccm.2021.04.010

Abstract

Women with cystic fibrosis (CF) face several unaddressed concerns related to their health. These areas of concern include explanations and guidance on a sex disparity in outcomes, timing of puberty, effects of contraception, prevalence of infertility and impact of pregnancy, and prevention of urinary incontinence and osteoporosis. These understudied topics leave women with numerous unanswered questions about how to manage sexual and reproductive health in the setting of CF. Because people with CF are living longer and healthier lives, there is an increasing awareness of these important aspects of care and multiple ongoing studies to address these understudied topics.

Keywords: Cystic fibrosis; Hormones; Menopause; Puberty; Sex differences; Sexual and reproductive health.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Cystic Fibrosis* / epidemiology
Cystic Fibrosis* / therapy
Female
Humans
Pregnancy
Reproductive Health