Summoning STRENGTH to Question the Placebo in REDUCE-IT

Circulation. 2021 Aug 10;144(6):407-409. doi: 10.1161/CIRCULATIONAHA.121.054539. Epub 2021 Aug 9.
No abstract available

Keywords: US Food and Drug Administration; fish oils; mineral oil; placebos; randomized controlled trials.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biomarkers
  • Fatty Acids, Omega-3* / administration & dosage
  • Fatty Acids, Omega-3* / adverse effects
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors* / administration & dosage
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors* / adverse effects
  • Placebo Effect*
  • Randomized Controlled Trials as Topic / methods*
  • Randomized Controlled Trials as Topic / standards*
  • Treatment Outcome

Substances

  • Biomarkers
  • Fatty Acids, Omega-3
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors