Maternal Nutrition Status Associated with Pregnancy-Related Adverse Outcomes

Nutrients. 2021 Jul 13;13(7):2398. doi: 10.3390/nu13072398.

Abstract

Although maternal nutrition has an impact on fetal development and gestational outcome, tracking maternal nutrition in outpatient practice is still complex and involves proper technical capacitation in this area. Nevertheless, the association between nutritional variables may broaden the ability to predict the occurrence of gestational disorders and prevention management. We aimed to identify factors that could indicate the probability of adverse outcomes in mid-pregnancy. From a cohort of 1165 nulliparous pregnant women without any previous disease, the nutritional status was assessed by body mass index (BMI) and mid-upper arm circumference (MUAC), associated with dietary patterns and sociodemographic characteristics. Two predictive models with nutritional status for screening the occurrence of adverse outcomes of preterm birth, gestational diabetes mellitus, small-for-gestational-age newborns and preeclampsia were developed. The odds of adverse outcomes were higher in non-white (p < 0.05) obese women and with high protein consumption. There was no significant difference between the models, with an overall accuracy of 63% for both models and a probability of success in predicting adverse outcomes (BMI = 61%, MUAC = 52%). This study of Brazilian pregnant nulliparous women offers two possible options for early tracking of adverse gestational outcomes that should be further externally validated.

Keywords: gestational diabetes mellitus; maternal nutrition; preeclampsia; preterm birth; small-for-gestational-age.

Publication types

  • Multicenter Study

MeSH terms

  • Birth Weight
  • Brazil
  • Diabetes, Gestational / etiology
  • Diet / adverse effects*
  • Feeding Behavior
  • Female
  • Gestational Age
  • Gestational Weight Gain
  • Humans
  • Infant, Newborn
  • Infant, Small for Gestational Age
  • Maternal Nutritional Physiological Phenomena*
  • Nutritional Status*
  • Nutritive Value
  • Pre-Eclampsia / etiology
  • Pregnancy
  • Pregnancy Complications / diagnosis
  • Pregnancy Complications / etiology*
  • Pregnancy Outcome
  • Premature Birth / etiology
  • Risk Assessment
  • Risk Factors