Lateral Ventricular Meningiomas: Clinical Features, Radiological Findings and Long-Term Outcomes

Haibo Teng; Zhiyong Liu; Ouying Yan; Wenbo He; Danyang Jie; Yuanwei Qie; Jianguo Xu

doi:10.2147/CMAR.S320651

Lateral Ventricular Meningiomas: Clinical Features, Radiological Findings and Long-Term Outcomes

Cancer Manag Res. 2021 Aug 4:13:6089-6099. doi: 10.2147/CMAR.S320651. eCollection 2021.

Authors

Haibo Teng^#¹, Zhiyong Liu^#¹, Ouying Yan², Wenbo He¹, Danyang Jie³, Yuanwei Qie⁴, Jianguo Xu¹

Affiliations

¹ Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
² Department of Radiation Oncology, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan, People's Republic of China.
³ Department of Neurosurgery, West China School of Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
⁴ Health Management Center, West-China Fourth Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.

^# Contributed equally.

Abstract

Purpose: Lateral ventricle meningioma (LVM) is a rare type of intracranial meningioma, which has been rarely studied. It has different clinical features, imaging features, and long-term results from other locations. This study investigated the epidemiology, clinical characteristics and prognosis of LVM and comprehensively describes its characteristics.

Methods: This article analyzes the LVMs that were diagnosed pathologically in West China hospital between January 1, 2009 and July 1 2020. Demographic information, imaging characteristics and prognostic factors are discussed. Data analysis was performed using SPSS 23.0 and R version 3.5.3.

Results: We collected 7202 meningiomas and 195 LVMs (136 females; median age, 46 years; range, 5-81 years) were included in this study. Gross total resection was completed in 189 patients. The OS rate was 93.8%, and the recurrence rate was 5.2%. Multivariate regression analysis showed that sex (P = 0.01) and tumor size (P = 0.018) were related to WHO grade. Postoperative KPS (P = 0.003) was associated with OS. WHO grade (P = 0.025), extent of tumor resection (P < 0.001), and hospital day (P=0.028) were associated with recurrence.

Conclusion: LVMs require long-term follow-up, individualized treatment, and follow-up strategies to be formulated according to the relevant risk factors.

Keywords: imaging features; lateral ventricular meningiomas; prognosis; recurrence.

Grants and funding

This work was supported by Key research and development project of science and technology department of Sichuan Province (2019YFS0392/3); 1.3.5 project for disciplines of excellence, West China Hospital, Sichuan University (ZYJC18007).