Molecularly Imprinted Polymers Coupled with Surface-Enhanced Raman Spectroscopy to Detect Chemical Hazards in Foods

Marti Z Hua; Shaolong Feng; Xiaonan Lu

doi:10.1007/978-1-0716-1629-1_11

Molecularly Imprinted Polymers Coupled with Surface-Enhanced Raman Spectroscopy to Detect Chemical Hazards in Foods

Methods Mol Biol. 2021:2359:131-139. doi: 10.1007/978-1-0716-1629-1_11.

Authors

Marti Z Hua¹, Shaolong Feng², Xiaonan Lu³

Affiliations

¹ Department of Food Science and Agricultural Chemistry, McGill University Macdonald Campus, Sainte-Anne-de-Bellevue, QC, Canada.
² Food, Nutrition, and Health Program, Faculty of Land and Food Systems, The University of British Columbia, Vancouver, BC, Canada.
³ Department of Food Science and Agricultural Chemistry, McGill University Macdonald Campus, Sainte-Anne-de-Bellevue, QC, Canada. [email protected].

PMID: 34410665
DOI: 10.1007/978-1-0716-1629-1_11

Abstract

Preparation of molecularly imprinted polymers coupled with surface-enhanced Raman spectroscopy (MIP-SERS) sensor and its application in detecting chemical hazards in food matrices are described. Sample cleaning is achieved by molecularly imprinted solid-phase extraction (MISPE), and target molecules are detected by SERS. Procedures of MIP synthesis, MISPE preparation, SERS substrate preparation, spectral collection, data analysis, and food analysis application are described.

Keywords: Chemical hazard detection; Food matrix; Food safety; Molecularly imprinted polymers; Molecularly imprinted solid-phase extraction; Sample preparation; Surface-enhanced Raman spectroscopy.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Molecular Imprinting*
Molecularly Imprinted Polymers
Solid Phase Extraction
Spectrum Analysis, Raman*

Substances

Molecularly Imprinted Polymers