The increasing trend of Type 2 diabetes in youth: An overview

Diabetes Metab Syndr. 2021 Sep-Oct;15(5):102253. doi: 10.1016/j.dsx.2021.102253. Epub 2021 Aug 18.

Abstract

Introduction: Pediatric Type 2 Diabetes Mellitus (T2DM) is increasing in incidence, largely in correlation with global childhood obesity crisis.

Complications: Early detection and treatment are vital as diabetes has been shown to progress rapidly and aggressively amongst children.

Etiology: Higher than expected insulin levels compared to adults, leads to more rapid β cell decline.

Treatments: New treatments to control glycemic levels among youth with T2DM are being evaluated. This review summarizes the current understanding of causes, complications, and treatments for youth diagnosed with T2DM. OR. Pediatric Type 2 Diabetes Mellitus (T2DM) is increasing in incidence, largely in correlation with the global childhood obesity crisis. With increase in cases comes new challenges for medical professionals. Early detection and treatment are vital as the disease has been shown to progress aggressively and bring complications to children at a rapid rate. New treatments are currently being studied to control glycemic levels among youth with T2DM, as current options are not as effective chronically in children as in adults. This review summarizes the current understanding of causes, complications, and treatments for youth diagnosed with T2DM.

Keywords: Adolescents; Children; Metformin; Obesity; T2DM.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Diabetes Mellitus, Type 2 / drug therapy
  • Diabetes Mellitus, Type 2 / epidemiology*
  • Diabetes Mellitus, Type 2 / pathology
  • Humans
  • Pediatric Obesity / physiopathology*
  • Risk Factors
  • Young Adult