Hyponatraemia due to the syndrome of inappropriate antidiuretic hormone secretion in adults with respiratory syncytial virus infection

Intern Med J. 2021 Aug;51(8):1340-1343. doi: 10.1111/imj.15453.

Abstract

We present a case of severe hyponatraemia due to syndrome of inappropriate antidiuretic hormone (SIADH) in a patient with respiratory syncytial virus (RSV) infection. A retrospective analysis of all patients admitted to our hospital with RSV in the preceding 3-year period revealed hyponatraemia in 41 (28%) cases, of which 13 (8.9%) were moderate or severe. SIADH was explored and confirmed in five (3.4%) patients, raising this as an important, previously unrecognised, complication of RSV infection in adults. Physician awareness of SIADH as a potential complication of RSV will facilitate early diagnosis and treatment of this potentially fatal disorder.

Keywords: hyponatraemia; respiratory syncytial virus; syndrome of inappropriate ADH secretion.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Humans
  • Hyponatremia* / diagnosis
  • Hyponatremia* / etiology
  • Hyponatremia* / therapy
  • Inappropriate ADH Syndrome* / complications
  • Inappropriate ADH Syndrome* / diagnosis
  • Respiratory Syncytial Virus Infections* / complications
  • Respiratory Syncytial Virus Infections* / diagnosis
  • Retrospective Studies
  • Vasopressins

Substances

  • Vasopressins