Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) kinetics remain understudied, including the impact of remdesivir. In hospitalized individuals, peak sputum viral load occurred in week 2 of symptoms, whereas viremia peaked within 1 week of symptom-onset, suggesting early systemic seeding of SARS-CoV-2. Remdesivir treatment was associated with faster viral decay.
Keywords: COVID-19; SARS-CoV-2; remdesivir; viral kinetics; viral load.
© The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America.