Severe hyperglycemia following transition from octreotide to lanreotide in a patient with enterocutaneous fistula receiving parenteral nutrition

Nutr Clin Pract. 2022 Jun;37(3):727-731. doi: 10.1002/ncp.10757. Epub 2021 Aug 31.

Abstract

Somatostatin analogues, suchas octreotide and lanreotide, are commonly used in the management of enterocutaneous fistula. We report a case of severe and prolonged hyperglycemia that occurred in a patient after receiving a one-time dose of lanreotide, who had previously been stable on octreotide and did not have a history of diabetes mellitus. Management of the patient's hyperglycemia while receiving parenteral nutrition is described.

Keywords: enterocutaneous fistula; hyperglycemia; parenteral nutrition; somatostatin analogue.

Publication types

  • Case Reports

MeSH terms

  • Diabetes Mellitus*
  • Humans
  • Hyperglycemia* / drug therapy
  • Hyperglycemia* / etiology
  • Intestinal Fistula* / drug therapy
  • Intestinal Fistula* / etiology
  • Octreotide / therapeutic use
  • Parenteral Nutrition
  • Peptides, Cyclic
  • Somatostatin / analogs & derivatives
  • Somatostatin / therapeutic use

Substances

  • Peptides, Cyclic
  • lanreotide
  • Somatostatin
  • Octreotide