Malignant carcinoma and skin melanoma neoplasms concomitantly in the thyroid

Ali Al-Harake; Israa Dandache; Hiba Moukadem; Marwan Saliba; Jimmy Chahine; Hosni Yazbeck; Fadi Abdel-Sater; Hussein Karnib; Mahmoud H Younes

doi:10.1002/ccr3.4790

Malignant carcinoma and skin melanoma neoplasms concomitantly in the thyroid

Clin Case Rep. 2021 Sep 15;9(9):e04790. doi: 10.1002/ccr3.4790. eCollection 2021 Sep.

Authors

Ali Al-Harake¹, Israa Dandache², Hiba Moukadem³, Marwan Saliba⁴, Jimmy Chahine¹, Hosni Yazbeck⁴, Fadi Abdel-Sater⁵, Hussein Karnib⁴, Mahmoud H Younes⁴

Affiliations

¹ Department of Surgery Al Rassoul Al Aazam Hospital Beirut Lebanon.
² Department of Life and Earth Sciences Faculty of Sciences I Lebanese University Beirut Lebanon.
³ Department of Oncology Saint George Hospital Baabda Lebanon.
⁴ Medical Research Center Al Rassoul Al Aazam Hospital Beirut Lebanon.
⁵ Department of Biochemistry Faculty of Sciences I Lebanese University Beirut Lebanon.

Abstract

Malignant melanomas metastatic to the thyroid gland are uncommon. Based on microscopy and DNA methylation profile, we report a rare coexistence of neoplasms in the thyroid, presumably in our case, with relapse-free condition on adjuvant therapy.

Keywords: DNA methylation; malignant melanoma; medullary thyroid carcinoma; prognosis; thyroid.

Publication types

Case Reports