The role of cord blood platelet gel in the management of a diabetic foot with tendon exposure

Regen Med. 2021 Nov;16(12):1051-1056. doi: 10.2217/rme-2021-0044. Epub 2021 Sep 24.

Abstract

Diabetic foot infection is frequent in diabetic patients and is due to neuropathy, trauma or peripheral arterial disease. The presence of an abscess requires urgent drainage and specific antibiotic therapy. Patients with critical limb ischemia need revascularization and, subsequently the intervention of a plastic surgeon is often required in cases of exposure of tendons and ligaments. During the COVID-19 pandemic, a patient was refered to our department with an abscess on the dorsum of the left foot. After urgent drainage with tendon exposure, he started specific antibiotic therapy and underwent tibial vessels angioplasty. After infection healing cord blood platelet gel was applied, accelerating the healing process, with injection of its liquid part into the exposed tendons, thus retaining the vital functions of the tendons.

Keywords: antibiotic therapy; cord blood platelet gel; diabetic foot infection; injections into tendons; peripheral revascularization; surgical debridements; wound healing.

MeSH terms

  • Amputation, Surgical
  • Blood Platelets
  • COVID-19*
  • Chronic Limb-Threatening Ischemia
  • Diabetes Mellitus*
  • Diabetic Foot* / therapy
  • Humans
  • Ischemia
  • Male
  • Pandemics
  • SARS-CoV-2
  • Tendons
  • Treatment Outcome