An infrequent etiology of Infective Endocarditis

Neeraj Goel; Prateek Shujanya; Jaswinder Kaur Oberoi; Arun Mohanty; Chand Wattal

doi:10.1016/j.ijmmb.2021.09.009

An infrequent etiology of Infective Endocarditis

Indian J Med Microbiol. 2021 Oct-Dec;39(4):540-541. doi: 10.1016/j.ijmmb.2021.09.009. Epub 2021 Sep 25.

Authors

Neeraj Goel¹, Prateek Shujanya², Jaswinder Kaur Oberoi³, Arun Mohanty⁴, Chand Wattal⁵

Affiliations

¹ Institute of Clinical Microbiology & Immunology, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, 110060, India. Electronic address: [email protected].
² Institute of Clinical Microbiology & Immunology, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, 110060, India. Electronic address: [email protected].
³ Institute of Clinical Microbiology & Immunology, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, 110060, India. Electronic address: [email protected].
⁴ Department of Cardiology, Sir Ganga Ram Hospital Rajinder Nagar, New Delhi, 110060, India. Electronic address: [email protected].
⁵ Institute of Clinical Microbiology & Immunology, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, 110060, India. Electronic address: [email protected].

PMID: 34583879
DOI: 10.1016/j.ijmmb.2021.09.009

Abstract

Abiotrophia. defectiva is an infrequent but an important cause of infectious endocarditis (IE). IE caused by A. defectiva may actually be more common than what is reported in the literature because of its failure to grown on routine media like blood agar and MacConkey agar, besides difficulty in its identification by conventional methods. IE by A. defectiva generally have more fulminant course and is associated with higher mortality and morbidity due to frequent embolic episodes and valvular tissue destruction. Ceftriaxone or vancomycin in combination with gentamicin and surgical replacement of valve is the recommended management.

Keywords: Abiotrophia defectiva; Infective endocarditis.

MeSH terms

Abiotrophia*
Agar
Anti-Bacterial Agents / therapeutic use
Endocarditis, Bacterial* / diagnosis
Endocarditis, Bacterial* / drug therapy
Gram-Positive Bacterial Infections* / diagnosis
Gram-Positive Bacterial Infections* / drug therapy
Humans

Substances

Anti-Bacterial Agents
Agar

Supplementary concepts

Abiotrophia defectiva