Delayed local reaction at a previous injection site reaction with dupilumab

Respirol Case Rep. 2021 Sep 21;9(10):e0852. doi: 10.1002/rcr2.852. eCollection 2021 Oct.

Authors

Toshiyuki Sumi^{1

2}, Yuta Nagahisa^{1

2}, Keigo Matsuura^{1

2}, Motoki Sekikawa^{1

2}, Yuichi Yamada^{1

2}, Hisashi Nakata¹, Hirofumi Chiba²

Affiliations

¹ Department of Pulmonary Medicine Hakodate Goryoukaku Hospital Hakodate Japan.
² Department of Respiratory Medicine and Allergology Sapporo Medical University School of Medicine Sapporo Japan.

Abstract

Clinicians should be aware that biologic agents, which include polysorbates, can cause delayed local skin reactions at a previous injection site.

Keywords: bronchial asthma; dupilumab; injection site reaction; polysorbate; severe asthma.

© 2021 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology.