Abstract
Sixteen patients, 14 with an infection of the lower respiratory tract and two with cholangitis, were treated with pefloxacin 400 mg bid or tid. The original pathogens were eradicated in all but one patient. Pefloxacin therapy resulted in clinical cure in 11 patients, three patients were improved clinically and in two patients a clinical failure was observed. No adverse effects were noticed during or after pefloxacin administration.
MeSH terms
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Adolescent
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Adult
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Aged
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Anti-Bacterial Agents / therapeutic use*
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Bacteria / drug effects
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Bacterial Infections / complications
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Bacterial Infections / drug therapy*
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Bacterial Infections / microbiology
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Bronchopneumonia / complications
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Bronchopneumonia / drug therapy*
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Bronchopneumonia / microbiology
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Cholangitis / complications
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Cholangitis / drug therapy*
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Cholangitis / microbiology
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Drug Evaluation
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Female
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Humans
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Intensive Care Units
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Male
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Middle Aged
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Norfloxacin / analogs & derivatives*
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Norfloxacin / therapeutic use
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Pefloxacin
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Pneumonia / complications
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Pneumonia / drug therapy*
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Pneumonia / microbiology
Substances
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Anti-Bacterial Agents
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Pefloxacin
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Norfloxacin