Innate Immunity

Bani Preet Kaur; Elizabeth Secord

doi:10.1016/j.iac.2021.07.003

Innate Immunity

Immunol Allergy Clin North Am. 2021 Nov;41(4):535-541. doi: 10.1016/j.iac.2021.07.003.

Authors

Bani Preet Kaur¹, Elizabeth Secord²

Affiliations

¹ Detroit Medical Center, Children's Hospital of Michigan, 3901 Beaubien Boulevard, Detroit, MI 48201, USA. Electronic address: [email protected].
² Department of Pediatrics, Children's Hospital of Michigan, Wayne State University, 3950 Beaubien Boulevard, Detroit, MI 48202, USA.

PMID: 34602226
DOI: 10.1016/j.iac.2021.07.003

Abstract

The innate immune response system forms an important line of defense by deploying a limited number of receptors specific for conserved microbial components. This deployment generates a rapid inflammatory response, while activating the adaptive immune system. Improvements in our understanding of the innate immune system have allowed us to explore various therapeutic strategies via modulation of the immune response.

Keywords: Anatomic barriers; Immune modulation; Inflammatory response; Innate immunity; Microbial defense; Physiologic barriers.

Publication types

Review

MeSH terms

Adaptive Immunity
Humans
Immune System*
Immunity, Innate*