Changes in Blood Biomarkers of Brain Injury and Degeneration Following Long-Duration Spaceflight

JAMA Neurol. 2021 Dec 1;78(12):1525-1527. doi: 10.1001/jamaneurol.2021.3589.

Abstract

This study investigates the longitudinal course of blood-based biomarkers representing the brain parenchyma in long-duration spaceflight.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amyloid beta-Peptides / blood
  • Biomarkers / blood*
  • Brain Injuries / blood*
  • Brain Injuries / etiology
  • Glial Fibrillary Acidic Protein / blood
  • Humans
  • Male
  • Middle Aged
  • Nerve Degeneration / blood*
  • Nerve Degeneration / etiology
  • Neurofilament Proteins / blood
  • Peptide Fragments / blood
  • Space Flight*

Substances

  • Amyloid beta-Peptides
  • Biomarkers
  • GFAP protein, human
  • Glial Fibrillary Acidic Protein
  • Neurofilament Proteins
  • Peptide Fragments
  • amyloid beta-protein (1-40)
  • neurofilament protein L