Mapping through somatic cell hybrids and cDNA probes of protein C to chromosome 2, factor X to chromosome 13, and alpha 1-acid glycoprotein to chromosome 9

Hum Genet. 1986 Sep;74(1):30-3. doi: 10.1007/BF00278781.

Abstract

The previously unassigned gene coding for the anti-coagulatory protein C has been mapped on chromosome 2 using a cDNA probe and genomic blots from a human-hamster somatic cell hybrid panel. The assignments of the genes coding for the coagulation factor X to chromosome 13, and for alpha 1-acid glycoprotein to chromosome 9 have been confirmed using a similar direct approach.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Line
  • Chromosome Mapping
  • Chromosomes, Human, Pair 13*
  • Chromosomes, Human, Pair 2*
  • Chromosomes, Human, Pair 9*
  • Cricetinae
  • Cricetulus
  • DNA / genetics
  • Factor X / genetics*
  • Genetic Markers
  • Humans
  • Hybrid Cells
  • Orosomucoid / genetics*
  • Protein C / genetics*

Substances

  • Genetic Markers
  • Orosomucoid
  • Protein C
  • Factor X
  • DNA