Diagnosis of Carney complex following multiple recurrent cardiac myxomas

Gen Thorac Cardiovasc Surg. 2022 Jan;70(1):87-91. doi: 10.1007/s11748-021-01719-w. Epub 2021 Oct 12.

Abstract

Carney complex is a rare syndrome caused by a genetic mutation leading to multiple endocrine abnormalities and a variety of tumors. Here, we report a case of Carney complex diagnosed due to recurrent multiple myxomas in the right atrium of a patient 16 years after the resection of the primary left atrial myxoma. Surgical excision was performed for the multiple recurrent right atrial tumors under cardiopulmonary bypass. The patient remained complication-free after surgery and was discharged on the 14th day. He was scheduled to continue echocardiographic follow-up and periodic systemic review by an endocrinologist. This case emphasizes the fact that if cardiac myxomas tend to be multiple and recurrent at a relatively young age, the possibility of Carney complex should be considered, even in the absence of any other related feature other than cardiac tumors.

Keywords: Carney complex; Cryoablation for myxoma; Recurrent of cardiac myxoma.

Publication types

  • Case Reports

MeSH terms

  • Carney Complex* / diagnosis
  • Carney Complex* / genetics
  • Carney Complex* / surgery
  • Heart Atria / diagnostic imaging
  • Heart Atria / surgery
  • Heart Neoplasms* / diagnostic imaging
  • Heart Neoplasms* / genetics
  • Heart Neoplasms* / surgery
  • Humans
  • Male
  • Myxoma* / diagnostic imaging
  • Myxoma* / genetics
  • Myxoma* / surgery
  • Neoplasm Recurrence, Local