Predictors of immediate neonatal outcome after cesarean section in Uganda

Int J Gynaecol Obstet. 2022 Jul;158(1):101-109. doi: 10.1002/ijgo.13986. Epub 2021 Nov 8.

Abstract

Objective: To identify predictors of low Apgar score, immediate neonatal death, and stillbirth after cesarean section in Uganda.

Methods: Records of cesarean sections performed at all 14 regional referral hospitals and also 14 first-level (district) hospitals in Uganda were reviewed. Both elective and emergency cases were included. Data comprised mother's age, indication, type of anesthesia, and immediate outcome of the newborn. To evaluate the relation of the predictor variables to outcome, regression analysis was performed.

Results: A total of 37 585 cesarean sections were recorded. The indications for cesarean section that led to the highest neonatal mortality and stillbirth rates and lowest mean Apgar scores were uterine rupture and hemorrhage. Emergency surgery and general anesthesia had worse neonatal outcomes than elective surgery and spinal anesthesia. Compared with general anesthesia, spinal anesthesia was favorable for neonatal outcomes.

Conclusion: Elective surgical planning and scale-up of the use of spinal anesthesia may potentially reduce stillbirths and immediate neonatal deaths.

Keywords: Apgar score; anesthesia; cesarean section; elective surgery; emergency surgery; neonatal death; stillbirth.

MeSH terms

  • Anesthesia, General / adverse effects
  • Anesthesia, Obstetrical*
  • Anesthesia, Spinal*
  • Apgar Score
  • Cesarean Section
  • Elective Surgical Procedures
  • Female
  • Humans
  • Infant, Newborn
  • Infant, Newborn, Diseases*
  • Perinatal Death*
  • Pregnancy
  • Stillbirth / epidemiology
  • Uganda / epidemiology