Preparation and evaluation of ultrasound-mediated dual-targeted theragnostic systems utilising phase-changeable polymeric nanodroplets on the integrin α_ν β₃ overexpressed breast cancer

Clin Transl Med. 2021 Oct;11(10):e607. doi: 10.1002/ctm2.607.

Authors

Na Li^{1

2}, Shaobo Duan¹, Yiwei Wang¹, Linlin Zhang¹, Yongqing Chen¹, Juan Zhang¹, Ruiqing Liu¹, Yaqiong Li¹, Luwen Liu¹, Shanshan Ren¹, Ye Zhang¹, Yuqi Guo^{1

2}, Zhenyu Ji³, Lianzhong Zhang¹

Affiliations

¹ Henan Provincial People's Hospital, People's Hospital of Henan University, People's Hospital of Zhengzhou University, Zhengzhou, PR China.
² Henan International Joint Laboratory for Gynecological Oncology and Nanomedicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, PR China.
³ Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, PR China.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Breast Neoplasms / diagnostic imaging*
Breast Neoplasms / drug therapy*
Breast Neoplasms / metabolism
Disease Models, Animal
Doxorubicin / administration & dosage*
Doxorubicin / metabolism
Female
Fluorocarbons / metabolism*
Humans
Integrins / metabolism*
Peptides / metabolism
Polymers / metabolism
Precision Medicine / methods
Rats
Rats, Sprague-Dawley
Theranostic Nanomedicine / methods*
Ultrasonography / methods*

Substances

Fluorocarbons
Integrins
Peptides
Polymers
Doxorubicin