Protein-protein interactions by influenza polymerase subunits as drug targets

Future Med Chem. 2022 Jan;14(2):53-56. doi: 10.4155/fmc-2021-0259. Epub 2021 Nov 3.

Authors

Tommaso Felicetti¹, Serena Massari¹

Affiliation

¹ Department of Pharmaceutical Sciences, University of Perugia, Perugia, 06123, Italy.

PMID: 34730024
DOI: 10.4155/fmc-2021-0259

No abstract available

Keywords: RNA-dependent RNA polymerase; antiviral agents; drug design; influenza virus; protein–protein interaction.

Publication types

Editorial
Research Support, Non-U.S. Gov't
Review

MeSH terms

Antiviral Agents / chemistry
Antiviral Agents / pharmacology*
Enzyme Inhibitors / chemistry
Enzyme Inhibitors / pharmacology*
Humans
Influenza A virus / drug effects*
Influenza A virus / enzymology
Microbial Sensitivity Tests
Protein Subunits / drug effects
RNA-Dependent RNA Polymerase / antagonists & inhibitors*
RNA-Dependent RNA Polymerase / chemistry
RNA-Dependent RNA Polymerase / metabolism

Substances

Antiviral Agents
Enzyme Inhibitors
Protein Subunits
RNA-Dependent RNA Polymerase