Successful treatment of cutaneous Acanthamoeba castellanii infection with miltefosine in a patient with chronic lymphocytic leukaemia on ibrutinib

Joanne S K Teh; Patrick C K Tam; Paul R Badenoch; Penelope J Adamson; Catriona Brennan; Gillian Marshman; David L Gordon

doi:10.1093/jac/dkab397

Successful treatment of cutaneous Acanthamoeba castellanii infection with miltefosine in a patient with chronic lymphocytic leukaemia on ibrutinib

J Antimicrob Chemother. 2022 Feb 2;77(2):539-541. doi: 10.1093/jac/dkab397.

Authors

Joanne S K Teh^{1

2}, Patrick C K Tam^{1

3}, Paul R Badenoch^{3

4}, Penelope J Adamson^{1

2

3}, Catriona Brennan^{2

5}, Gillian Marshman⁶, David L Gordon^{1

2

3}

Affiliations

¹ Department of Microbiology and Infectious Diseases, Flinders Medical Centre, Flinders Drive, Bedford Park, South Australia 5042, Australia.
² SA Pathology, Flinders Medical Centre, Flinders Drive, Bedford Park, South Australia 5042, Australia.
³ College of Medicine and Public Health, Flinders University, Sturt Road, Bedford Park, South Australia 5042, Australia.
⁴ Department of Ophthalmology, Flinders Medical Centre, Flinders Drive, Bedford Park, South Australia 5042, Australia.
⁵ Department of Anatomical Pathology, Flinders Medical Centre, Flinders Drive, Bedford Park, South Australia 5042, Australia.
⁶ Department of Dermatology, Flinders Medical Centre, Flinders Drive, Bedford Park, South Australia 5042, Australia.

PMID: 34747467
DOI: 10.1093/jac/dkab397

No abstract available

Publication types

Letter

MeSH terms

Acanthamoeba castellanii*
Adenine / analogs & derivatives
Humans
Leukemia, Lymphocytic, Chronic, B-Cell* / complications
Leukemia, Lymphocytic, Chronic, B-Cell* / drug therapy
Phosphorylcholine / analogs & derivatives
Piperidines / therapeutic use

Substances

Piperidines
Phosphorylcholine
ibrutinib
miltefosine
Adenine