A modulator-bound GPCR structure enables allosteric non-opioid analgesia

Nat Struct Mol Biol. 2021 Nov;28(11):871-872. doi: 10.1038/s41594-021-00681-8.

David F Lee^{1

2

3

4}, Matan Geron^{1

2

3}, Grégory Scherrer^{5

6

7

8}

¹ Department of Cell Biology and Physiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
² UNC Neuroscience Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
³ Department of Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
⁴ Pharmacology Curriculum, Biological & Biomedical Sciences Program, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
⁵ Department of Cell Biology and Physiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. [email protected].
⁶ UNC Neuroscience Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. [email protected].
⁷ Department of Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. [email protected].
⁸ New York Stem Cell Foundation-Robertson Investigator, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. [email protected].

No abstract available

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