Synchronized Nasal Intermittent Positive Pressure Ventilation

Corrado Moretti; Camilla Gizzi

doi:10.1016/j.clp.2021.07.005

Synchronized Nasal Intermittent Positive Pressure Ventilation

Clin Perinatol. 2021 Dec;48(4):745-759. doi: 10.1016/j.clp.2021.07.005. Epub 2021 Oct 2.

Authors

Corrado Moretti¹, Camilla Gizzi²

Affiliations

¹ Department of Paediatrics, Policlinico Umberto I, Sapienza University of Rome, Viale Regina Elena 324, Rome 00185, Italy.
² Paediatric and Neonatology Unit, "Sandro Pertini" Hospital, Via Monti Tiburtini 385, Rome 00157, Italy. Electronic address: [email protected].

PMID: 34774207
DOI: 10.1016/j.clp.2021.07.005

Abstract

Avoiding MV is a critical goal in neonatal respiratory care. Different modes of noninvasive respiratory support beyond nasal CPAP, such as nasal intermittent positive pressure ventilation (NIPPV) and synchronized NIPPV (SNIPPV), may further reduce intubation rates. SNIPPV offers consistent benefits over nonsynchronized techniques such as a more efficient positive pressure transmission to the lung, an effective increase in transpulmonary pressure during ventilation, and a better stabilization of the chest wall during inspiration. This review discusses mechanisms of action, benefits and limitations of synchronized noninvasive ventilation, describes the different modes of synchronization, and analyzes properties and clinical results.

Keywords: Noninvasive ventilation; Preterm infant; RDS; Synchronized NIPPV.

Publication types

Review

MeSH terms

Continuous Positive Airway Pressure
Humans
Infant, Newborn
Infant, Premature
Intermittent Positive-Pressure Ventilation
Noninvasive Ventilation*
Respiratory Distress Syndrome, Newborn* / therapy