Epigenetic mechanisms underpinning sexual dimorphism in lung disease

Epigenomics. 2022 Jan;14(2):65-67. doi: 10.2217/epi-2021-0400. Epub 2021 Nov 22.

Abstract

Tweetable abstract Important differences in lung disease exist between males and females in symptoms, course of disease and therapeutic response due to molecular, genetic and epigenetic mechanisms related to biological sex.

Keywords: X chromosome; estrogen; innate immunity; miRNA; microbial endocrinology; sex hormones.

Publication types

  • Editorial

MeSH terms

  • Epigenesis, Genetic
  • Female
  • Humans
  • Lung Diseases* / genetics
  • Male
  • Sex Characteristics*