Freeform optics enable irregular system geometries and high optical performance by leveraging rotational variance. To this point, for both imaging and illumination, freeform optics has largely been synonymous with freeform surfaces. Here a new frontier in freeform optics is surveyed in the form of freeform gradient-index (F-GRIN) media. F-GRIN leverages arbitrary three-dimensional refractive index distributions to impart unique optical influence. When transversely variant, F-GRIN behaves similarly to freeform surfaces. By introducing a longitudinal refractive index variation as well, F-GRIN optical behavior deviates from that of freeform surfaces due to the effect of volume propagation. F-GRIN is a useful design tool that offers vast degrees of freedom and serves as an important complement to freeform surfaces in the design of advanced optical systems for both imaging and illumination.