High serum copeptin may be a marker of an increased carotid intima-media thickness in asymptomatic patients with type 1 diabetes

J Diabetes Complications. 2022 Jan;36(1):108085. doi: 10.1016/j.jdiacomp.2021.108085. Epub 2021 Nov 11.

Abstract

We aimed to study the association of copeptin with carotid intima-media thickness in 60 patients with type 1 diabetes (T1DM-patients). Our results suggest that copeptin might improve the stratification of cardiovascular risk in T1DM-patients. Further research is needed to determine the value in identifying carotid disease of this biochemical marker.

Keywords: Atherosclerosis; cardiovascular disease; carotid intima-media thickness; carotid plaques; copeptin; type 1 diabetes; vasopressin.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biomarkers
  • Carotid Artery Diseases* / complications
  • Carotid Artery Diseases* / diagnostic imaging
  • Carotid Intima-Media Thickness
  • Diabetes Mellitus, Type 1* / complications
  • Diabetes Mellitus, Type 2* / complications
  • Glycopeptides
  • Humans
  • Risk Factors

Substances

  • Biomarkers
  • Glycopeptides
  • copeptins