A computational study of the relation between the power density in the tumor and the maximum temperature in the scalp during Tumor Treating Fields (TTFields) therapy

Nichal Gentilal; Ariel Naveh; Tal Marciano; Zeev Bomzon; Yevgeniy Telepinsky; Yoram Wasserman; Pedro Cavaleiro Miranda

doi:10.1109/EMBC46164.2021.9630071

A computational study of the relation between the power density in the tumor and the maximum temperature in the scalp during Tumor Treating Fields (TTFields) therapy

Annu Int Conf IEEE Eng Med Biol Soc. 2021 Nov:2021:4192-4195. doi: 10.1109/EMBC46164.2021.9630071.

Authors

Nichal Gentilal, Ariel Naveh, Tal Marciano, Zeev Bomzon, Yevgeniy Telepinsky, Yoram Wasserman, Pedro Cavaleiro Miranda

PMID: 34892148
DOI: 10.1109/EMBC46164.2021.9630071

Abstract

In this work we investigated the relation between the power density in the tumor and the maximum temperature reached in the scalp during TTFields treatment for glioblastoma. We used a realistic head model to perform the simulations in COMSOL Multiphysics and we solved Pennes' equation to obtain the temperature distribution. Our results indicate that there might be a linear relation between these two quantities and that TTFields are safe from a thermal point of view.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Brain Neoplasms* / therapy
Electric Stimulation Therapy*
Glioblastoma* / therapy
Humans
Scalp
Temperature