A case of multisystem inflammatory syndrome in adults following natural infection and subsequent immunization

Anthony Lieu; Jordan Mah; Deirdre Church

doi:10.1016/j.ijid.2021.12.339

A case of multisystem inflammatory syndrome in adults following natural infection and subsequent immunization

Int J Infect Dis. 2022 Mar:116:34-37. doi: 10.1016/j.ijid.2021.12.339. Epub 2021 Dec 24.

Authors

Anthony Lieu¹, Jordan Mah², Deirdre Church³

Affiliations

¹ Division of Infectious Diseases, Department of Medicine, Cummings School of Medicine, University of Calgary, Calgary, Alberta, Canada. Electronic address: [email protected].
² Division of Microbiology, Department of Pathology, Cummings School of Medicine, University of Calgary, Calgary, Alberta, Canada.
³ Division of Infectious Diseases, Department of Medicine, Cummings School of Medicine, University of Calgary, Calgary, Alberta, Canada; Division of Microbiology, Department of Pathology, Cummings School of Medicine, University of Calgary, Calgary, Alberta, Canada.

Abstract

Multisystem inflammatory syndrome in adults is a rare and life-threatening complication that follows natural COVID-19 infection and primarily affects young unvaccinated adults. This complication is seldom described following vaccination, which would have important implications for the vaccination timing and platform in this population. COVID-19 vaccines are extremely effective; however, the risk of rare adverse events needs to be balanced with the vaccination benefits.

Keywords: Adult multisystemic inflammatory diseases COVID-19 related; COVID-19 vaccines; Interleukin-1 receptor antagonist protein; MIS-A; Multi-inflammatory system in adults; SARS-CoV-2; Systemic inflammatory response syndrome.

Publication types

Case Reports

MeSH terms

Adult
COVID-19 Vaccines* / adverse effects
COVID-19*
Humans
Immunization
SARS-CoV-2
Systemic Inflammatory Response Syndrome / diagnosis
Systemic Inflammatory Response Syndrome / etiology
Vaccination / adverse effects

Substances

COVID-19 Vaccines