Complex translocation t(8;12;14) in a cell line derived from a child with nonendemic Burkitt-type acute lymphoblastic leukemia

Cancer Genet Cytogenet. 1987 Sep;28(1):145-53. doi: 10.1016/0165-4608(87)90364-5.

Abstract

A cell line is described with a typical Burkitt lymphoma (BL) marker 14q+ due to the classical reciprocal translocation between chromosome #8 and #14 with breakpoints at 8q24.1 and 14q32.3. In addition, an interstitial piece from the long arm of 12(q24.1-q24.3) is inserted at the site of the exchange on chromosome #8, proximal to 14q32.3.

Publication types

  • Case Reports

MeSH terms

  • B-Lymphocytes
  • Burkitt Lymphoma / genetics*
  • Cell Line
  • Child
  • Chromosome Banding
  • Chromosomes, Human, Pair 12*
  • Chromosomes, Human, Pair 14*
  • Chromosomes, Human, Pair 8*
  • Genetic Markers
  • Humans
  • Karyotyping
  • Leukemia, Lymphoid / genetics*
  • Male
  • Translocation, Genetic*

Substances

  • Genetic Markers