RADIOTHERAPY OF PROSTATE CANCER: PRIMARY RADIOTHERAPY AND RADIOTHERAPY IN DISEASE RELAPSE

Acta Clin Croat. 2019 Nov;58(Suppl 2):46-59. doi: 10.20471/acc.2019.58.s2.08.

Abstract

Radiotherapy presents one of the essential modes of treatment in patients with prostate cancer at almost any stage of the disease. It can be delivered as external beam radiotherapy, as brachytherapy or two methods combined. Higher radiation doses are proven to be more effective than low doses and moderate hypofractionation with doses up to 3.4 Gy per fraction is proven equivalent to standard fractionation using 1.8- 2 Gy per fraction. Stereotactic body radiotherapy (SBRT) with doses from 3.4 to 7.25 Gy per fraction presents valuable option in certain subgroups of patients. In case of local regional disease relapse, radiotherapy is used in curative setting.

Keywords: brachytherapy; hypofractionation; prostate cancer; radiotherapy; salvage radiotherapy; stereotactic body radiotherapy.

Publication types

  • Review