A PARTHENOGENESIS allele from apomictic dandelion can induce egg cell division without fertilization in lettuce

Nat Genet. 2022 Jan;54(1):84-93. doi: 10.1038/s41588-021-00984-y. Epub 2022 Jan 6.

Abstract

Apomixis, the clonal formation of seeds, is a rare yet widely distributed trait in flowering plants. We have isolated the PARTHENOGENESIS (PAR) gene from apomictic dandelion that triggers embryo development in unfertilized egg cells. PAR encodes a K2-2 zinc finger, EAR-domain protein. Unlike the recessive sexual alleles, the dominant PAR allele is expressed in egg cells and has a miniature inverted-repeat transposable element (MITE) transposon insertion in the promoter. The MITE-containing promoter can invoke a homologous gene from sexual lettuce to complement dandelion LOSS OF PARTHENOGENESIS mutants. A similar MITE is also present in the promoter of the PAR gene in apomictic forms of hawkweed, suggesting a case of parallel evolution. Heterologous expression of dandelion PAR in lettuce egg cells induced haploid embryo-like structures in the absence of fertilization. Sexual PAR alleles are expressed in pollen, suggesting that the gene product releases a block on embryogenesis after fertilization in sexual species while in apomictic species PAR expression triggers embryogenesis in the absence of fertilization.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Apomixis / genetics*
  • Cell Division / genetics*
  • Clustered Regularly Interspaced Short Palindromic Repeats
  • Genes, Plant*
  • Lactuca / genetics*
  • Lactuca / growth & development
  • Ovum / cytology
  • Taraxacum / genetics*
  • Transcriptome
  • Zinc Fingers / genetics