A Prospective Study of Costs Associated With the Evaluation of Allergic Reactions to Radiological Contrast Media

J Investig Allergol Clin Immunol. 2023 Apr 18;33(2):102-108. doi: 10.18176/jiaci.0774. Epub 2022 Jan 14.

Abstract

Background and objective: The prevalence of hypersensitivity reactions to radiological contrast media (RCM) is increasing owing to the improved performance of diagnostic and therapeutic tests that require RCMs. Objective: We carried out a year-long real-life observational study to prospectively evaluate patients referred to the allergy department from primary care, the emergency department, and other specialties with suspected moderate-to-severe RCM hypersensitivity reactions.

Methods: To study the costs of evaluating RCM hypersensitivity reactions, we systematically recorded direct and indirect costs.

Results: Sixty-nine patients with previous reactions to RCM were evaluated in the allergy department from June 1, 2017, to May 31, 2018.Total direct health care costs were €10 715.84, with a mean (SD) cost per patient of €155.30 (77.08). Specifically, direct non-health care costs reached €1605.42 (mean, €23.27 [41.14]), and indirect costs were €6490.85 (mean, €94.07 [110.61]). In summary, the total cost was €18 812.11, that is, a mean cost of €272.64 (164.77).

Conclusion: Our study shows that the costs of an elective evaluation of hypersensitivity reactions to RCM are low, thus confirming that correct and safe management of affected patients are cost-effective. Therefore, our efforts should be directed toward ensuring the necessary logistics.

Keywords: Contrast media; Diagnostic tests; Health care costs; Hypersensitivity; Prospective studies.

Publication types

  • Observational Study

MeSH terms

  • Contrast Media / adverse effects
  • Drug Hypersensitivity* / diagnosis
  • Drug Hypersensitivity* / epidemiology
  • Humans
  • Hypersensitivity* / diagnosis
  • Hypersensitivity* / epidemiology
  • Prospective Studies
  • Skin Tests

Substances

  • Contrast Media