Rapid Detection and Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Omicron Variant in a Returning Traveler

Clin Infect Dis. 2022 Aug 24;75(1):e350-e353. doi: 10.1093/cid/ciac032.

Abstract

We describe rapid detection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant using targeted spike single-nucleotide polymorphism polymerase chain reaction and viral genome sequencing. This case occurred in a fully vaccinated and boosted returning traveler with mild symptoms who was identified through community surveillance rather than clinical care.

Keywords: Omicron; SARS-CoV-2; genomic surveillance; multiplex PCR; vaccine.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.
  • Research Support, N.I.H., Intramural
  • Research Support, Non-U.S. Gov't
  • Research Support, N.I.H., Extramural

MeSH terms

  • COVID-19* / diagnosis
  • Genome, Viral
  • Humans
  • Polymerase Chain Reaction
  • SARS-CoV-2* / genetics

Supplementary concepts

  • SARS-CoV-2 variants