Tics in a patient with Parkinson's disease

Mov Disord. 1986;1(1):79-83. doi: 10.1002/mds.870010111.

Abstract

A patient with Gilles de la Tourette syndrome later developed Parkinson's disease in middle age. This was accompanied by a marked reduction in the frequency of tics but levodopa toxicity exacerbated the tics. The dopamine hypothesis of tic disorders is supported by this observation.

Publication types

  • Case Reports

MeSH terms

  • Humans
  • Levodopa / adverse effects
  • Male
  • Middle Aged
  • Parkinson Disease / complications*
  • Parkinson Disease / drug therapy
  • Receptors, Dopamine / physiology
  • Tourette Syndrome / chemically induced
  • Tourette Syndrome / complications*
  • Tourette Syndrome / physiopathology

Substances

  • Receptors, Dopamine
  • Levodopa