Retrospective observational study of patient outcomes with local wound infusion vs epidural analgesia after open hepato-pancreato-biliary surgery

BMC Anesthesiol. 2022 Jan 18;22(1):26. doi: 10.1186/s12871-022-01563-2.

Abstract

Background: Epidural analgesia is conventionally used as the mainstay of analgesia in open abdominal surgery but has a small life-changing risk of complications (epidural abscesses or haematomas). Local wound-infusion could be a viable alternative and are associated with fewer adverse effects.

Methods: A retrospective observational analysis of individuals undergoing open hepato-pancreato-biliary surgery over 1 year was undertaken. Patients either received epidural analgesia (EP) or continuous wound infusion (WI) + IV patient controlled anaesthesisa (PCA) with an intraoperative spinal opiate. Outcomes analyzed included length of stay, commencement of oral diet and opioid use.

Results: Between Jan 2016- Dec 2016, 110 patients were analyzed (WI n=35, EP n=75). The median length of stay (days) was 8 in both the WI and EP group (p=0.846), the median time to commencing oral diet (days) was 3 in WI group and 2 in EP group (p=0.455). There was no significant difference in the amount of oromorph, codeine or tramadol (mg) between WI and EP groups (p=0.829, p=0.531, p=0.073, respectively).

Conclusions: Continuous wound infusion + IV PCA provided adequate analgesia to patients undergoing open hepato-pancreato-biliary surgery. It was non-inferior to epidural analgesia with respect to hospital stay, commencement of oral diet and opioid use.

Keywords: Epidural; HPB surgery; Wound infusion catheter.

Publication types

  • Comparative Study
  • Observational Study

MeSH terms

  • Aged
  • Analgesia, Epidural / methods*
  • Analgesia, Patient-Controlled / methods
  • Analgesics, Opioid / administration & dosage*
  • Anesthetics, Local / administration & dosage*
  • Digestive System Surgical Procedures / methods*
  • Female
  • Humans
  • Infusions, Parenteral
  • Length of Stay / statistics & numerical data
  • Male
  • Middle Aged
  • Pain Management / methods
  • Pain, Postoperative / drug therapy*
  • Patient Satisfaction / statistics & numerical data
  • Retrospective Studies
  • Treatment Outcome

Substances

  • Analgesics, Opioid
  • Anesthetics, Local