An outbreak of acute Lantana camara poisoning in cattle is described in which 10 out of 91 animals died. The affected cattle became icteric and voided soft, black faeces. Necropsies were performed on three steers, and the macro- and microscopical changes in their livers and kidneys were compatible with those of L. camara poisoning. Changes were similar in two steers that developed typical signs after being dosed with fresh L. camara collected in the toxic camp. Clinical pathological changes in experimental animals included elevated serum urea and creatinine concentrations.