Modeling the Impact of Vaccination Strategies for Nursing Homes in the Context of Increased Severe Acute Respiratory Syndrome Coronavirus 2 Community Transmission and Variants

Inga Holmdahl; Rebecca Kahn; Kara Jacobs Slifka; Kathleen Dooling; Rachel B Slayton

doi:10.1093/cid/ciac062

Modeling the Impact of Vaccination Strategies for Nursing Homes in the Context of Increased Severe Acute Respiratory Syndrome Coronavirus 2 Community Transmission and Variants

Clin Infect Dis. 2022 Aug 24;75(1):e880-e883. doi: 10.1093/cid/ciac062.

Authors

Inga Holmdahl¹, Rebecca Kahn^{1

2}, Kara Jacobs Slifka², Kathleen Dooling², Rachel B Slayton²

Affiliations

¹ Center for Communicable Disease Dynamics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USAand.
² COVID-19 Response, US Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Abstract

Using an agent-based model, we examined the impact of community prevalence, the Delta variant, staff vaccination coverage, and booster vaccines for residents on outbreak dynamics in nursing homes. Increased staff coverage and high booster vaccine effectiveness leads to fewer infections, but cumulative incidence is highly dependent on community transmission.

Keywords: Covid-19; booster dose; nursing homes; vaccination.

Published by Oxford University Press for the Infectious Diseases Society of America 2022.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

COVID-19* / prevention & control
Humans
Nursing Homes
SARS-CoV-2*
Vaccination

Supplementary concepts

SARS-CoV-2 variants

Grants and funding

U01 CA261277/CA/NCI NIH HHS/United States