A Population-Level Study Concerning the Assumed Association Between Suicide Rates and Antidepressant Consumption in Hungary

Omega (Westport). 2024 May;89(1):122-137. doi: 10.1177/00302228211067031. Epub 2022 Jan 29.

Abstract

Background: It has been claimed that the advent of modern antidepressants has reduced the suicide rate.

Aims: To examine the correlation between the suicide rate and the prescription of antidepressants.

Method: A dynamic regression was employed to analyze a 73-month-long, monthly time series between 2010 and 2016 in Hungary. The independent variable was the Defined Daily Dose value for the number of antidepressant (AD) prescriptions filled each month.

Results: The models failed to show a significant association between the prescription of antidepressants and age- and sex-specific monthly suicide rates.

Conclusions: The prescription of antidepressants in Hungary has had no impact on suicide rates.

Keywords: Granger causality; antidepressants; autoregressive integrated moving average; dynamic regression; suicide.

MeSH terms

  • Antidepressive Agents / therapeutic use
  • Female
  • Humans
  • Hungary
  • Male
  • Suicide*

Substances

  • Antidepressive Agents