From "More is Better" to "Less is More": A Commentary on Antimicrobial Use in Pediatric Oncology

J Pediatric Infect Dis Soc. 2022 May 30;11(5):229-238. doi: 10.1093/jpids/piab111.

Abstract

Reducing avoidable antimicrobial exposure to pediatric patients with cancer is achievable and necessary to promote optimal short- and long-term outcomes. Multiple evidence-based practices are already well established but should be more consistently implemented. Important opportunities exist to further improve the evidence to guide selective antimicrobial use in pediatric oncology.

Keywords: antimicrobial stewardship; change management; febrile neutropenia; hospital oncology service; pediatrics.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Anti-Infective Agents* / therapeutic use
  • Child
  • Humans
  • Neoplasms* / drug therapy

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents