Post-prostate biopsy acute bacterial prostatitis and screening cultures using selective media: An overview

Int J Urol. 2022 Jun;29(6):486-493. doi: 10.1111/iju.14824. Epub 2022 Feb 10.

Abstract

The development of several culture media and the availability to isolate and treat pathogens prior to a surgical procedure give us the ability to minimize treatment-related complications, and ultimately results in better outcomes for patients and avoidance of unwanted post-procedure inpatient admissions. In the last decade, an increasing incidence of multidrug-resistant Escherichia coli, especially extended-spectrum beta-lactamase-producing E. coli and fluoroquinolone-resistant pathogens, has been reported. These resistant species frequently colonize the rectal flora and gain access to the systemic circulation via the rectal plexus following a prostate biopsy. The bacteria can eventually lead to life-threatening complications, which is especially important in high-risk patients with multiple co-morbidities. Previously published studies have focused on the isolation of these pathogens with selective media before an invasive procedure and the potential benefits of incorporating the use of selective media as a mandatory pre-operative step. This preventive measure will allow us to offer a tailored prophylactic treatment that benefits patients and reduces the economic burden for the hospital.

Keywords: biopsy; culture; prostatitis; screening; selective medium.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use
  • Antibiotic Prophylaxis / methods
  • Biopsy / adverse effects
  • Drug Resistance, Bacterial
  • Escherichia coli
  • Escherichia coli Infections* / epidemiology
  • Humans
  • Male
  • Prostate / pathology
  • Prostatitis* / drug therapy
  • Rectum / microbiology

Substances

  • Anti-Bacterial Agents