Elevated blood monocyte counts in alcohol-associated hepatitis

JGH Open. 2022 Jan 27;6(2):148-151. doi: 10.1002/jgh3.12707. eCollection 2022 Feb.

Abstract

In this retrospective study of 164 patients with alcohol-associated hepatitis, we find that the mean absolute monocyte count is 0.95 thousand cells/L, which is significantly higher than the upper limit of normal (0.80 thousand cells/μL) (P < 0.0001). Monocyte count is correlated with disease severity as measured by MELD score (R = 0.400, P < 0.0001) and Maddrey discriminant function (R = 0.330, P < 0.0001).

Keywords: alcoholic liver disease; hepatic inflammation; liver immunobiology.