PCSK9 participates in oxidized-low density lipoprotein-induced myocardial injury through mitochondrial oxidative stress and Drp1-mediated mitochondrial fission

Clin Transl Med. 2022 Feb;12(2):e729. doi: 10.1002/ctm2.729.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Dynamins / genetics
  • Dynamins / metabolism*
  • Dynamins / pharmacology
  • Humans
  • Lipoproteins, LDL / adverse effects*
  • Lipoproteins, LDL / genetics
  • Mitochondrial Dynamics / physiology
  • Myocardium / enzymology*
  • Myocardium / immunology
  • Oxidative Stress / physiology
  • Proprotein Convertase 9 / adverse effects*
  • Proprotein Convertase 9 / genetics

Substances

  • Lipoproteins, LDL
  • oxidized low density lipoprotein
  • PCSK9 protein, human
  • Proprotein Convertase 9
  • DNM1L protein, human
  • Dynamins