Effect of Sunitinib Treatment on Skin Sodium Accumulation in Patients With Renal Cancer: a Pilot Study

Lajos Markó; Anne Dörr; Peter Linz; Anton H van den Meiracker; Ingrid M Garrelds; Titus Kuehne; Ralf Dechend; A H Jan Danser; Anne Flörcken; Dominik N Müller

doi:10.1161/HYPERTENSIONAHA.122.19079

Effect of Sunitinib Treatment on Skin Sodium Accumulation in Patients With Renal Cancer: a Pilot Study

Hypertension. 2022 May;79(5):e103-e105. doi: 10.1161/HYPERTENSIONAHA.122.19079. Epub 2022 Feb 22.

Authors

Lajos Markó^{1

2

3}, Anne Dörr⁴, Peter Linz^{5

6}, Anton H van den Meiracker⁷, Ingrid M Garrelds⁷, Titus Kuehne^{8

9}, Ralf Dechend^{1

3

10

11}, A H Jan Danser⁷, Anne Flörcken^{4

12}, Dominik N Müller^{1

2

3

10}

Affiliations

¹ Experimental and Clinical Research Center, a cooperation of Charité - Universitätsmedizin Berlin and Max Delbrück Center for Molecular Medicine, Berlin, Germany (L.M., R.D., D.N.M.).
² DZHK (German Centre for Cardiovascular Research), partner site Berlin, Germany (L.M., D.M.N.).
³ Berlin Institute of Health (BIH), Germany (L.M., R.D., D.N.M.).
⁴ Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Hematology, Oncology, and Tumor Immunology, Campus Virchow-Klinikum, Berlin (A.D., A.F.).
⁵ Institute of Radiology (P.L.), Friedrich-Alexander-University Erlangen-Nürnberg, Germany.
⁶ Department of Nephrology and Hypertension, Friedrich-Alexander-University Erlangen-Nürnberg, Germany (P.L).
⁷ Division of Pharmacology and Vascular Medicine, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (A.H.v.d.M., I.M.G., A.H.J.D.).
⁸ Institute for Cardiovascular Computer-assisted Medicine, Charité - Universitätsmedizin Berlin, Germany (T.K.).
⁹ German Heart Center Berlin, Germany (T.K.).
¹⁰ Charité - Universitätsmedizin Berlin, Germany (L.M., R.D., D.N.M.).
¹¹ Helios Clinic Berlin-Buch, Germany (R.D.).
¹² German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, Germany (A.F.).

PMID: 35189705
DOI: 10.1161/HYPERTENSIONAHA.122.19079

No abstract available

Keywords: blood pressure; homeostasis; hypertension; skin; sodium; sunitinib; vascular endothelial growth factor c.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Antineoplastic Agents* / therapeutic use
Carcinoma, Renal Cell* / drug therapy
Female
Humans
Kidney Neoplasms* / drug therapy
Male
Pilot Projects
Pyrroles / therapeutic use
Sodium
Sunitinib / therapeutic use

Substances

Antineoplastic Agents
Pyrroles
Sodium
Sunitinib