Cerebellar liponeurocytoma with an unusual metastatic CSF spinal seeding

Background: Cerebellar liponeurocytoma is rare intracranial tumor appearing mostly in the posterior fossa.

Case description: We hereby report a long follow-up of a case of cerebellar liponeurocytoma in a 60-year-old female. At first, she presented in March of 2010 with the symptoms of hydrocephalus and was found to have a lesion located in the fourth ventricle. The tumor was resected with a small remnant around the brainstem which grew on serial imaging. Due to slow tumor growth, the patient was treated with conformal radiotherapy and was kept under follow-up with both outpatient visits and serial brain imaging. In 2018, due to low back pain and lumbar radicular pain, a new set of images of the spine was obtained which revealed multilevel intradural tumor spinal dissemination. The patient further underwent an open spinal biopsy at the level of L5 which revealed the same pathology of the intracranial tumor. The patient went on to receive total spine irradiation.

Conclusion: This case report describes a rare metastatic phenomenon to the spinal cord of the exact same pathology and grade of an intracranial cerebellar liponeurocytoma tumor.