Nuclear envelope assembly and dynamics during development

Bernhard Hampoelz; Janina Baumbach

doi:10.1016/j.semcdb.2022.02.028

Nuclear envelope assembly and dynamics during development

Semin Cell Dev Biol. 2023 Jan 15:133:96-106. doi: 10.1016/j.semcdb.2022.02.028. Epub 2022 Mar 4.

Authors

Bernhard Hampoelz¹, Janina Baumbach²

Affiliations

¹ Department of Molecular Sociology, Max Planck Institute of Biophysics, Max-von-Laue-Strasse 3, 60438 Frankfurt am Main, Germany. Electronic address: [email protected].
² Department of Molecular Sociology, Max Planck Institute of Biophysics, Max-von-Laue-Strasse 3, 60438 Frankfurt am Main, Germany; Structural and Computational Biology Unit, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany.

PMID: 35249812
DOI: 10.1016/j.semcdb.2022.02.028

Abstract

The nuclear envelope (NE) protects but also organizes the eukaryotic genome. In this review we will discuss recent literature on how the NE disassembles and reassembles, how it varies in surface area and protein composition and how this translates into chromatin organization and gene expression in the context of animal development.

Keywords: Embryogenesis; Nuclear envelope; Nuclear lamina; Nuclear pore complex.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Eukaryotic Cells*
Genome
Nuclear Envelope* / metabolism