Rhabdomyosarcoma in low- and middle-income countries: A report from the Asociacion de Hemato-oncología Pediatrica de Centro América (AHOPCA)

Pediatr Blood Cancer. 2023 Aug;70(8):e29669. doi: 10.1002/pbc.29669. Epub 2022 Mar 16.

Abstract

This report describes the results of an observational study dedicated to rhabdomyosarcoma developed by the Asociación de Hemato-oncología Pediatrica de Centro América (AHOPCA) between 2001 and 2018. Overall, 337 previously untreated patients < 18 years old were included in the analysis; 58% had unresected disease, and 19% were metastatic at diagnosis. With a median follow-up of 6.6 years, five-year event-free and overall survival rates were 30% and 33%, respectively. Local progression/relapse was the main cause of treatment failure.

Keywords: AHOPCA; low- and middle-income countries; outcome; protocol; rhabdomyosarcoma; treatment.

Publication types

  • Observational Study

MeSH terms

  • Adolescent
  • Cancer Care Facilities
  • Developing Countries*
  • Humans
  • Infant
  • Neoplasm Recurrence, Local / therapy
  • Rhabdomyosarcoma* / epidemiology
  • Rhabdomyosarcoma* / therapy
  • Treatment Failure