Complete resolution of alopecia totalis following chemotherapy for B-cell acute lymphoblastic leukemia

Pediatr Dermatol. 2022 Jul;39(4):655-656. doi: 10.1111/pde.14977. Epub 2022 Mar 16.

Abstract

Alopecia totalis (AT) is a cosmetically debilitating chronic disease characterized by non-scarring hair loss of the entire scalp. The clinical course of AT is highly unpredictable, and effective durable treatment options are limited. The resolution of alopecia has been reported post-autologous and allogeneic hematopoietic stem cell transplantation; however, no cases of AT remission following chemotherapy alone have been described. Herein, we present a case of complete remission of AT following chemotherapy for B-cell acute lymphoblastic leukemia in a pediatric patient.

Keywords: alopecia; autoimmunity; chemotherapy; leukemia; pediatrics.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Alopecia Areata* / drug therapy
  • Child
  • Hematopoietic Stem Cell Transplantation*
  • Humans
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma* / drug therapy
  • Remission Induction
  • Transplantation, Autologous