Infusion of haploidentical NKG2D-CAR-T_CD45RA- cells in two pediatric patients with advanced relapsed and refractory acute leukemia was safe but achieved no clinical benefits

Affiliations

• ¹ Hematological Malignancies Lab-H12O Clinical Research Unit, Spanish National Cancer Research Center (CNIO), Madrid, Spain.
• ² Pediatric Hemato-Oncology Department, La Paz University Hospital, Madrid, Spain.
• ³ Translational Research Group in Pediatric Oncology Hematopoietic Transplantation and Cell Therapy, La Paz University Hospital Institute for Health Research-IdiPAZ, Madrid, Spain.
• ⁴ Pediatric Department, Autonomous University of Madrid, Madrid, Spain.
• ⁵ Pediatric Molecular Hemato-Oncology Department, Medical and Molecular Genetics Institute (INGEMM), La Paz University Hospital, Madrid, Spain.
• ⁶ Advanced Therapy Medicinal Products Production Unit, Pediatric Hemato-Oncology Service and Pharmacy Service, La Paz University Hospital, Madrid, Spain.
• ⁷ Hematology and Hemotherapy Department, La Paz University Hospital, Madrid, Spain.
• ⁸ Hematology Department, 12 de Octubre University Hospital, Madrid, Spain.
• ⁹ Tumor Immune Activation and Evasion Group, National Biotechnology Center, Madrid, Spain.