Towards depeptidized aminoboronic acid derivatives through the use of borylated iminium ions

Chem Commun (Camb). 2022 Apr 19;58(32):5033-5036. doi: 10.1039/d2cc00659f.

Abstract

Herein, we use α-boryl iminium intermediates to access progressively depeptidized branched β-aminoboronic acids that are functionalized with biologically relevant heterocycles. We investigate the interaction of these novel compounds with carbohydrates under physiological conditions and demonstrate their potential as synthetic building blocks.

MeSH terms

  • Boronic Acids*
  • Carbohydrates*
  • Ions

Substances

  • Boronic Acids
  • Carbohydrates
  • Ions